Abstract:Abstract:Objective To explore the clinical influencing factors of the pregnancy outcomes in artificial insemination by donor (AID). Methods A retrospective study was performed to analyze the pregnancy outcomes of AID for 660 infertile couples in 1 305 treatment cycles from 2015 to 2018 in Fujian Provincial Maternity and Child Health Hospital. The relationship between influencing factors(maternal age,duration of infertility,BMI,endometrial thickness and location of insemination)and AID outcomes was analyzed. Results Single factor analysis showed that pregnancy rate of maternal aged ≤25 (31.7%) was higher than that of aged 2535 (22.8%),the aged ≥35 (19.4%) decreased more obviously. The pregnancy rate of maternal infertility duration ≤5 years (24.8%) was higher than that of >5 years (18.6%). The pregnancy rate in intrauterine insemination (IUI) group (26.2%) was high than that of intracervical insemination (ICI) group (15.6%). The maternal age and location of insemination were the key influencing factors of pregnancy rate of AID by multivariate logistic regression analysis. Conclusion The AID pregnancy rates of AID decreased with the maternal ages, pregnancy rate of AID was higher for young woman and the method with IUI.